I CONSCIOUSNESS: PERMANENT MENTAL ENHANCEMENT
THE MECHANISM OF HOW CONSCIOUSNESS PROFOUNDLY EFFECTS DNA EVOLUTIONARY CHANGES MAY HAVE BEEN REVEALED IN A RECENT STUDY.
IN KEEPING WITH THE BASIC PREMISE OF THIS WEBSITE, THAT CONSCIOUSNESS IS NOT MANIFESTED BY THE BRAIN, BUT IS AN OUTSIDE AWARENESS THAT INFORMS THE BRAIN AND PROMOTES ITS EVOLUTIONARY PROGRESSION, THE FOLLOWING REFERENCED PAPER MAY PROVIDE THE MECHANISM OF THIS PHENOMENON
A recent paper from the laboratories of the Gladstone Institute whose Director and Senior Investigator, Dr. Lennart Mucke, and his group discovered a profound mechanism that may have evolutionary significance. Though the original premise of this investigation by the nine participant scientists was related to Alzheimer’s disease and its amyloid-B protein, a diversity of other experiments in this study had surprising new discoveries. (1)
As part of study, the scientists analyzed young adult mice after they were placed into new, larger cages with different toys and odors. They were allowed to explore this new environment for only two hours.Thereafter, they measured their brain levels of a protein known as gamma-H2AX. This brain protein accumulates when breaks occur in double-stranded molecules of DNA. Breaks in one strand occur quite frequently, but breaking both is usually indicative of a diseased state. Unexpectedly, the researcher found that the breaks in the neurons of the healthy “Explorer Mice” had up to six more breaks than the mice that stayed in their home cages. These DNA breaks were completely healed within 24 hours due to the DNA repair mechanism within the cells.
Dr. Mucke stated that “ breaks of double strands of DNA seem to a part of normal brian activity”. These DNA breaks occurred in various regions of the brain, especially in “the dentate gyrus”, an area of spatial memory. “ It may be part of normal learning “ said neuroscientist, Dr Fred Gage, of the Salk Institute, who was not part of this study.There was some indication that Dr. Mucke’s laboratory would further investigate this phenomenon.
In 1835 Charles Darwin and other members of the crew of the”Beagle” the renown expedition ship, discovered on the Galapagos Islands, a finding that to this day profounds the scientific community relative to evolutionary diversity in a tiny geographic area. Darwin and his crew members collected 15 closely related species of Finches and introduced them to a mystified scientific community. The genetic code would not be discovered well over a century in the future.
In the current speculation relative to the phenomenon of Darwin’s Finches, there has been a recognition of the evolution of cognitive behaviors. Adding to the attempt of obtaining a clearer picture of how the dramatic changes in this single species are the applicable studies of these islands biodiversities, mechanisms of speciation and hybridization, principles of beak-jaw biomechanics, as well as the underlying developmental “Genetic Mechanism” in generating morphological diversity. (2)
The premise herein is that the outside environment witch includes conscious awareness has profound effects upon the DNA of all specie’s brains. The changes in the way the DNA assembles its ultimate molecules are beholden to these phenomenon. This concept provides the impetus for EVOLUTIONARY PROGRESSION.
III EPIGENETICS: NUTRITIONAL SOURCES AFFECTING PROGENY PERMANENTLY
Epigenetic is the study heritable changes in gene expression that “DO NOT” alter DNA sequences. The outside forces that cause changes in the gene expression are not permanent mutations, nonetheless, these forces orchestrates how a DNA molecules unwinds its various sections to make new proteins or even new cells. Epigenetics effects take place within the Chromatin DNA (Gene) complex and the histone proteins that the DNA are wrapped around. The result of these modifications can have profound effects on the template that will produce different amino acids, proteins, cells, and may ultimately affect the total organism without having any “Gene Mutation”.(3)
This phenomenon has been seen in almost all species studied, and may be a vital functional survival mechanism, which includes humans. Radical changes in climate could bring about bring about epigenetic survival affects. However, nutritional studies in laboratory animals, statistical analyses in human populations, have seen dramatic changes generated in the progeny of those species studied.
Diets poor in protein, fats, carbohydrates, vitamins and minerals and/or, sparse amounts of available food has been shown in a myriad of diverse animal studies not only to greatly affect the subject animals, but also at the “least several generations of their progeny”. In-utero disturbance of developing fetuses may portend a compromised future is considered an epigenetic effect, without DNA mutations.(4)
SUMMARIZING THE DESCRIPTION OF THREE EVOLUTIONARY
PROCESSES HEREIN ARE:
I. CONSCIOUSNESS: How the brain gains new knowledge and memory
II. PHYSICAL CHANGES: from environmental diversity
III TOTAL ORGANISM CHANGES: Fro environment and nutrition
- 1. Suberbielle, Elsa. el at. Physiological brain activities causes DNA double-strand breaks in neurons, with exacerbation by amyloid-B. Nature Neuroscience (2013) doi.1038/nn.3356.
- 2. Abzhanov, Arhat. Darwin’s Galapagos finches in modern biology. Phil. Trans. R. Soc. B.(2010) 365 1001-1007.
- 3. Jablonka,E and Raz G.,Transgenerational epigenetic inheritance: prvalence,mechanisms, and implications for the study of heredity and evolution. Q Rev Boil 2009 Jun;84(2): 131-76.
- 4. Dermal, A J and Jirtie, R A. Epigenetic Disruption: The Effect of Early Developmental Exposures.
Birth Defects RevA Clin mol Teratol, 2010 October; 88(10) 938-944.